Delivery remains a black box.

Bonito is building the data foundation for programmable oligonucleotide delivery. Our platform combines functional selections with giga-scale encoded libraries to generate proprietary biological datasets that drive an iterative AI-enabled discovery loop. With these tools, Bonito discovers highly potent delivery ligands and therapeutics while learning the rules that govern their success.

Platform

Better signal to noise

Bonito has re-built encoded library technologies and live cell selection technologies from the ground up, specifically for delivery ligand discovery.

Encoded Librariesgiga-scale molecular diversity
Functional Selectionsselect for what really matters - delivery
AI-Enablinghigh dimensional data for delivery biology
Therapeutic Focus

Oligotherapeutic delivery to any cell or tissue type

Small molecule and antibody agents, selected for functional uptake and paired with oligotherapeutic payloads.

Small molecule ligands
Low molecular weight delivery systems, designed for your cell target of interest.
Antibody agent ligands
Antibody fragments and bispecifics, unlocking the hardest delivery challenges.
Novel delivery gateways
Target agnostic approaches to identify the best access points into cells.